Scientific Development
Translate promising concepts into differentiated products with practical technical plans, assays, and preclinical strategies.
PRODUCT STRATEGY · TRANSLATIONAL RESEARCHRegenerative Medicine · Orthobiologics · Biomaterials
Helping Clients Translate Scientific Innovation into Clinically Meaningful Solutions
Applied Regeneration LLC helps innovators in regenerative medicine, biomaterials, and tissue-based products optimize scientific, product-development, and regulatory decisions by reducing uncertainty and managing risk on the path toward clinical and commercial application.
Experience Brought to Engagements
Technical depth.
Regulatory judgment.
Commercial perspective.
20+Years in
regenerative medicine
20+U.S. patents
14Publications
4FDA-cleared platforms
Integrated Capabilities
From Scientific Promise to
Product Reality
An integrated approach to product development, regulatory strategy, and commercialization planning—realizing opportunity through informed decisions that reduce uncertainty and support thoughtful risk management.
Regulatory Strategy
Navigate device, HCT/P, and combination-product pathways with decisions grounded in product science and market reality.
FDA 510(k) · SECTION 361 HCT/PCommercial Translation
Align technical positioning, manufacturing, licensing, and commercialization so strong science leads to market success.
MARKET POSITIONING · LICENSINGContract R&D
Advance programs through hands-on execution in BSL-1 and BSL-2 capable wet-lab facilities in Pasadena, California.
ASEPTIC PROCESSING · ANALYTICAL TESTING
The Product Journey
Decisions get harder where disciplines meet
Orthobiologic technologies rarely fit neatly within scientific, regulatory, or commercial boundaries. Applied Regeneration integrates these perspectives early to reduce uncertainty and realize opportunity.
Discuss Your Program →
- 01Evaluate — Find the differentiated product thesis
Technology assessment, technical due diligence, risk mapping, and market positioning.
- 02Develop — Build the evidence and development plan
Assays, preclinical strategy, biomaterial characterization, and regulatory alignment.
- 03Translate — Move with confidence toward market
Manufacturing transfer, licensing support, commercialization, and launch readiness.
Deep Domain Focus
Specialized where biology, materials, and devices converge
Grounded in decades of hands-on experience with growth factors, biomaterials, tissue technologies, implants, and advanced delivery systems.
01Bone Regeneration02Orthobiologics03Synthetic Bone Grafts04Bioactive Biomaterials05Tissue-Based Technologies06BMP Delivery Systems07Implant Surface Engineering08Combination Products09Manufacturing Scale-Up10Technology Licensing
Founder Track Record
Representative Accomplishments
FDA 510(k)TechnologyRepresentative Contributions
K082615Grafton II Enhanced DBM (MagniFuse®)
Conceived the product concept and led scientific development of this procedure-specific DBM platform through FDA clearance.
K121316Alpine Adjustable Implant System
Identified titanium plasma spray (TPS) as the preferred surface roughening technology following characterization of osteoblast responses in tissue culture.
K171495Zyston Strut 3D-Printed Titanium Cage
Diagnosed prototype fracture failures via SEM/EDS, traced the cause to print-media contamination, and resolved it—keeping the program on track.
K203218CaP Sphere Pellet Pack Synthetic Bone Void Filler
Developed the formulation, final product configuration, and delivery system, and supported manufacturing scale-up and technical market positioning.
Wet Lab Research Capability
Strategy informed by experimental reality
Our research facility in Pasadena, California, supports BSL-1 and BSL-2 tissue culture studies, aseptic sample processing, biochemical and analytical testing, and cell-based assays—ensuring program decisions are grounded in experimental evidence.
Founder & Principal
Keyvan Behnam, Ph.D., MBA
More than two decades advancing regenerative medicine and orthobiologics from discovery through FDA clearance and commercialization.
Keyvan has held scientific leadership roles at Zimmer Biomet, Biomet, Lanx, Osteotech, and Intuitive Biotechnologies. He holds a Ph.D. in Physiological Science from UCLA, where he trained under Dr. Marshall R. Urist in the characterization, regulation, and delivery of bone morphogenetic proteins, along with an MBA in Finance and a B.S. in Bioengineering from UC Berkeley.
He is also Founder and Managing Director of Applied Regenerative Therapeutics, a division and trade name of Applied Regeneration LLC.
20+U.S. Patents14Publications & ChaptersUCLAPh.D. Training
A New Chapter in Product Development
Applied Regenerative Therapeutics
A Product Development Division of Applied Regeneration LLC
Applied Regeneration LLC has launched Applied Regenerative Therapeutics to advance internally developed regenerative-medicine technologies toward clinical and commercial application. ART complements ARLLC's consulting and contract-research activities with an internally focused product-development platform.
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